“Creatine is more and more understood to be arguably a very powerful complement individuals can take for total well being, and this patent provides to the mounting analysis underscoring its significance,” mentioned Mark Faulkner, founder and president of Vireo Methods. “I’m excited concerning the transformative potential this analysis has on the flexibility to strengthen the immune system and battle viruses, in addition to on different fields of well being.”
Registered with the U.S. Patent and Trademark workplace, the patent protects the corporate’s creatine formulations to be used in immune help therapies and merchandise for the following 20 years.
The patent analysis
The patent relies on analysis initiated in the course of the pandemic and features a main cell tradition research performed with the College of Manitoba, together with contributions to most cancers research at UCLA and Vanderbilt that yielded constant findings associated to the activation of T cells via creatine compounds. The core of the medical analysis is detailed within the patent software.
In short, Vireo Methods defined that its creatine hydrochloride (HCL) “facilitates the entry of antiviral substances into cells, strengthening the physique’s virus-fighting functionality whereas minimizing irritation brought on by viral proteins”. The analysis additionally reveals that creatine and comparable compounds present the physique with the power to mount a robust immune response towards viral infections.
The corporate attributes this functionality to what it claims is vastly enhanced bioavailability of its creatine HCL in comparison with commonplace creatine monohydrate. Its improved solubility and permeability resulted in 70% extra absorption into the bloodstream, in response to findings from a 2013 research led by Donald Miller, PhD, professor in pharmacology and therapeutics on the College of Manitoba and Vireo Methods board member.
“Different types of creatine would possibly probably provide immune help if they might successfully attain the bloodstream,” Faulkner mentioned. “Nevertheless, what units CON-CRĒT Creatine HCL aside is its exceptional capacity to attain superior absorption in comparison with older creatine formulations (i.e., creatine monohydrate).”
Forthcoming analysis will embrace animal testing to additional reveal the efficacy of sure compounds towards viruses and to optimize dosing and formulation by utilizing a mixture of creatine conjugations to supply higher and focused immune help.
“The way forward for creatine remedy for immune well being will undoubtedly draw closely from the information offered on this patent,” Faulkner added. “Moreover, we anticipate the upcoming follow-on patent, anticipated to be granted subsequent 12 months, will delve deeper into the mobile energetics influenced by creatine, enabling cells to perform extra successfully and preserve higher total well being and resilience.”
First immune complement with creatine
Vireo Methods, primarily based in Nashville, TN, launched a multi-ingredient method in 2020 as “the primary immune help complement with creatine” underneath newly developed product division Promera Well being Immune Assist, however Faulkner mentioned that the corporate determined to modify gears given creatine’s potential as a novel standalone immune well being ingredient.
“We swiftly redirected our focus away from Promera Well being Immune Assist—and to the brand new analysis —as a result of it fell inside a extremely aggressive market section, and its effectiveness could possibly be attributed to the a number of helpful elements it contained.”
Along with CON-CRĒT, the method included immune boosters like Vitamin D, zinc, selenium, black elderberry and inexperienced tea extracts in addition to Alpha-GEE, Vireo System’s patented amino acid-based peptide that helps wholesome irritation responses.
“This considerably obscured the exceptional efficacy and significance of the creatine element inside the method,” Faulkner added. “We consider that the creatine is the first driver behind the substantial and overarching constructive influence on the immune system’s Killer T Cells, and we wished to emphasise its essential function with out dilution from different elements.”
Future creatine-powered immune help merchandise will launch underneath the Vireo and CON-CRĒT product traces.
